fa انگل شناسی Parasitology مروري Review Article <div> <ol style="list-style-type:upper-alpha;"> <li value="531761952"></li> </ol> <strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Background and Objectives</strong>: <em>Staphylococcus aureus </em>is a common cause of nosocomial infections. The ability of <em>S. aureus </em>to form biofilm and acquire antimicrobial resistance has made this organism a major health problem. In this study, we investigate the biofilm-forming ability of <em>S. aureus </em>isolates from clinical samples.<span dir="RTL"></span><br> <strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Methods:</strong> Sixty <em>S. aureus</em> isolates from clinical specimens were collected from the 5th Azar Hospital of Gorgan (Iran) in 2018. The isolates were identified using conventional methods including Gram staining and biochemical tests (catalase and coagulase). Biofilm formation by <em>S. aureus </em>isolates was evaluated using a microplate-based method.<br> <strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Results:</strong> Of 60 <em>S. aureus</em> isolates, 47 (78.3%) strains were identified as biofilm-forming and 13 (21.7%) strains were non-biofilm-forming.<br> <strong>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Conclusion: </strong>The high prevalence of biofilm-producing <em>S. aureus</em> isolates in the 5^th Azar hospital of Gorgan could pose a major health challenge with serious consequences for hospitalized patients. Therefore, it is crucial to disinfect and sterilize hospital surfaces and equipment effectively to minimize the risk of contamination and spread of bacteria in the hospital settings.<br> &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; <strong>Keywords: </strong>Biofilms, <em>Staphylococcus aureus</em>, sample.</div> Biofilms, Staphylococcus aureus, sample. 14 16 http://mlj.goums.ac.ir/browse.php?a_code=A-10-736-1&slc_lang=fa&sid=1 Abolfazl Khandandel 100319475328460015833 100319475328460015833 No Department of Microbiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran Hami Kaboosi 100319475328460015834 100319475328460015834 Yes Department of Microbiology, Ayatollah Amoli Branch, Islamic Azad University, Amol, Iran Ailar Jamalli 100319475328460015835 100319475328460015835 No Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran Fatemeh Peyravii Ghadikolaii 100319475328460015836 100319475328460015836 No Department of Biology, Ghaemshahr Branch, Islamic Azad University, Ghaemshahr, Iran